Seminar: Fluorescent Sensor Development for Almost Everything
posted by Department of Chemistry for HKU and Public
Event Type: Public Lecture/Forum/Seminar/Workshop/Conference/Symposium
Event Nature: Science & Technology
Prof. Young-Tae Chang
Department of Chemistry,
National University of Singapore
Conventional sensor development requires defining the target and design of sensor, which is so-called hypothesis driven approach. While powerful, this approach cannot be applied to unknown target or difficult to be applied to complex of analytes. To overcome the limitation, we have devised a Diversity Oriented Fluorescence Library Approach (DOFLA) where a combinatorial synthesis of fluorescent dye is combined with unbiased screening to accelerate the sensor development. More than 10,000 synthetic organic dyes were constructed as a tool box, and numerous analytes have been tested, yielding systematic platform for sensor development for almost everything. Not only physical analytes, phantom target such as “temperature” is also pursued with biological application. Complex or unknown target problem with biological systems were also challenged, and various cell type selective probes for live bioimaging were developed. The sensors and probes developed in this study will be freely available for the chemical and biological community for common usage.
All are Welcome
Tea will be served at 17:15 in the Departmental Lobby on the G/F, Chong Yuet Ming Chemistry Building
|Venue||Lecture Theatre P1, CYM Chemistry Building|
Registration is not required.
Should you have any enquiries, please feel free to contact Lam Chak Fung Daniel by email at email@example.com